Diabetes and Alzheimers Disease in the Uniform Data Set 

 
   Lead Investigator:    Mary Sano
   Institution      :    Mount Sinai
   E-Mail           :    mary.sano@mssm.edu
   Proposal ID      :    10


   Publications:


1  Nandipati S, Luo X, Schimming C, Grossman H, Sano M
   Cognition in Non-Demented Diabetic Older Adults
   Journal Article  Curr Aging Sci,5:131-135,2012,PMC3659164

   PUBLISHED



2  Zhu CW, Grossman H, Schimming C, Sano M
   Non-Amnestic Deficit Characterizes the Cognitive Profile in Diabetes: Results from National Alzheimer's Coordinating Center's Uniform Data Set (NACC UDS)
   Abstract  Alzheimers Dement,13:P484-P485,2017,

   PUBLISHED



3  Zhu CW, Luo X, Schimming C, Grossman H, Sano M
   Longitudinal effects of diabetes on cognitive decline: Results from the National Alzheimer's Coordinating Center's Uniform Data Set (NACC UDS)
   Abstract  Alzheimers Dement,12:P1175,2016,

   PUBLISHED





   Proposal Description:
   Objective:  To determine the impact of diabetes on clinical status in patients with Alzheimer???s Disease. Specifically we will examine differences that exist at baseline and the impact that diabetes has on progression over a one year period.  Specific Aims / Research Question / Hypotheses:  Specific Aim 1: Diabetic??? AD subjects will demonstrate poorer clinical baseline status including cognitive (MMSE and CDR), behavioral (GDS and NPIQ) and functional (FAQ) outcomes than non-diabetic AD subjects.  Specific Aim 2: Diabetic??? AD subjects with diabetes will demonstrate greater deterioration in clinical status including cognitive (??MMSE and CDR), behavioral (??GDS and ??NPIQ) and functional (??FAQ) outcomes over a one year period than non-diabetic AD subjects. (??X = X1-X0: difference in test X between time 1 and time 0).